Publications

Degree of immobilization of synthetic RGDS(PO3H2)PA peptides on titanium surfaces
Abe Y, Okazaki Y, Hiasa K, Hirata I, Yoshida Y, Taji T, Suzuki K, Okazaki M, Akagawa Y
Dent. Mater. J. 29:668‒672 (2010)

Chemical analyses of hydroxyapatite formation on SAM surfaces modified with COOH, NH2, CH3, and OH functions
Hirata I, Akamatsu M, Fujii E, Poolthong S, Okazaki M
Dent. Mater. J. 29:438‒445 (2010)

2009

Hyaluronic acid hydrogel loaded with genetically-engineered brain-derived neurotrophic factor as a neural cell carrier
Nakaji-Hirabayashi T, Kato K, Iwata H
Biomaterials 30:4581–4589 (2009)

Enhanced survival of neural cells embedded in hydrogels composed of collagen and laminin-derived cell adhesive peptide
Hiraoka M, Kato K, Nakaji-Hirabayashi T, Iwata H
Bioconjugate Chem. 20:976–983 (2009)

Surface-displayed antibodies as a tool for simultaneously controlling the arrangement and morphology of multiple cell types with microscale precision
Miyazaki H, Maki T, Kato K, Iwata H
ACS Appl. Mater. Interfaces 1:53–55 (2009)

Surface-anchoring of spontaneously dimerized epidermal growth factor for highly selective expansion of neural stem cells
Nakaji-Hirabayashi T, Kato K, Iwata H
Bioconjugate Chem. 20:102–110 (2009)

Prolonged durability of electroporation microarrays as a result of addition of saccharides to nucleic acids
Fujimoto H, Kato K, Iwata H
Anal. Bioanal. Chem. 393:607–614 (2009)

Bone formation ability of carbonate apatite-collagen scaffolds with different carbonate contents

Matsuura A, Kubo T, Doi K, Hayashi K, Morita K, Yokota R, Hayashi H, Hirata I, Okazaki M, Akagawa Y

Dent. Mater. J. 28:234‒242 (2009)

2008

Electroporation microarray for parallel transfer of small interfering RNA into mammalian cells
Fujimoto H, Kato K, Iwata H
Anal. Bioanal. Chem. 392:1309–1316 (2008)

Essential role of structural integrity and firm attachment of surface-anchored epidermal growth factor in adherent culture of neural stem cells
Nakaji-Hirabayashi T, Kato K, Iwata H
Biomaterials 29:4403–4408 (2008)

A collagen-binding mimetic of neural cell adhesion molecule
Miyazaki H, Kato K, Teramura Y, Iwata H
Bioconjugate Chem. 19:1119–1123 (2008)

Self-assembling chimeric protein for the construction of biodegradable hydrogels capable of interaction with integrins expressed on neural stem/progenitor cells
Nakaji-Hirabayashi T, Kato K, Iwata H
Biomacromolecules 9:1411–1416 (2008)

Multifunctional chimeric proteins for the sequential regulation of neural stem cell differentiation
Nakaji-Hirabayashi T, Kato K, Arima Y, Iwata H
Bioconjugate Chem. 19:516–524 (2008)

Use of microarrays in transfection of mammalian cells with dicer-digested small interfering RNAs
Fujimoto H, Kato K, Iwata H
Anal. Biochem. 374:417–422 (2008)

High-throughput cytometry using antibody arrays

Kato K, Ko IK, Ishimuro T, Toda M, Arima Y, Hirata I, Iwata H

Biomaterials in Asia T. Tateishi, ed., 2008, World Scientific Publishing Co Pte Ltd., Singapore, pp. 506–516

Higher concentrations of fluoride ions dramatically inhibit the survival of osteoblasts
Hirata I, Okazaki M
J. Oral Tissue Eng. 6:3‒8 (2008)

Influence of chlorine dioxide on cell death and cell cycle of human gingival fibroblasts
Nishikiori R, Nomura Y, Sawajiri M, Masuki K, Hirata I, Okazaki M
J. Dent. 36:993‒998 (2008)

Influence of the chemical structure of functional monomers on their adhesive performance
Van Landuyt KL, Yoshida Y, Hirata I, Snauwaert J, de Munck J, Okazaki M, Suzuki K, Lambrechts P, Van Meerbeek B
J. Dent. Res. 87:757‒761 (2008)

Complement activation on surfaces carrying amino groups
Toda M, Kitazawa T, Hirata I, Hirano Y, Iwata H
Biomaterials 29:407‒417 (2008)

2007

High-throughput immunophenotyping by surface plasmon resonance imaging
Kato K, Ishimuro T, Hirata I, Arima Y, Iwata H
Anal. Chem. 79:8616–8623 (2007)

Ultrastructural study on the specific binding of genetically engineered epidermal growth factor to type I collagen fibrils
Kato K, Sato H, Iwata H
Bioconjugate Chem. 18:2137–2143 (2007)

Array-based functional screening for genes that regulate vascular endothelial differentiation of Flk1-positive progenitors derived from embryonic stem cells
Yamauchi F, Okada M, Kato K, Martin JL, Iwata H
Biochim. Biophys. Acta, General Subjects 1770:1085–1097 (2007)

Oriented immobilization of epidermal growth factor onto culture substrates for the selective expansion of neural stem cells
Nakaji-Hirabayashi T, Kato K, Arima Y, Iwata H
Biomaterials 28:3517–3529 (2007)

Antibody arrays for quantitative immunophenotyping
Kato K, Toda M, Iwata H
Biomaterials 28:1289–1297 (2007)

Combinatorial protein display for the cell-based screening of biomaterials that direct neural stem cell differentiation
Nakajima M, Ishimuro T, Kato K, Ko I-K, Hirata I, Arima Y, Iwata H
Biomaterials 28:1048–1060 (2007)

Apoptotic and necrotic influence of dental resin polymerization initiators in human gingival fibroblast cultures
Masuki K, Nomura Y, Bhawal UK, Sawajiri M, Hirata I, Nahara Y, Okazaki M
Dent. Mater. J. 26:861‒869 (2007)

Cell adhesion and proliferation patterns on mixed self-assembled monolayers carrying various ratios of hydroxyl and methyl groups
Fuse Y, Hirata I, Kurihara H, Okazaki M
Dent. Mater. J. 26:814‒819 (2007)

Acceleration of bone formation with BMP2 in frame-reinforced CO3Ap-collagen sponge scaffolds
Hirata I, Nomura Y, Ito M, Shimazu A, Okazaki M
J. Artif. Organs 10:212‒217 (2007)

Synthetic osteopontin-derived peptide SVVYGLR can induce neovascularization in artificial bone marrow scaffold biomaterials
Hamada Y, Egusa H, Kaneda Y, Hirata I, Kawaguchi N, Hirao T, Matsumoto T, Yao M, Daito K, Suzuki M, Yatani H, Daito M, Okazaki M, Matsuura N
Dent. Mater. J. 26:487‒492 (2007)

Immobilization of simulated reducing agent at the surface of SiO2 fillers in dental composite resins
Shibata S, Hirata I, Nomura Y, Shirai K, Fujitani M, Shintani H, Okazaki M
Dent. Mater. J. 26:568‒574 (2007)

2006

Fabrication of cell-based microarrays using micropatterned alkanethiol monolayers for the parallel silencing of specific genes by small-interfering RNA
Fujimoto H, Yoshizako S, Kato K, Iwata H
Bioconjugate Chem. 17:1404–1410 (2006)

Layer-by-layer assembly of cationic lipid and plasmid DNA onto gold surface for stent-assisted gene transfer
Yamauchi F, Koyamatsu Y, Kato K, Iwata H
Biomaterials 27:3497–3504 (2006)

Analysis of chemical interaction of 4-MET with hydroxyapatite using XPS
Nagakane K, Yoshida Y, Hirata I, Fukuda R, Nakayama Y, Shirai K, Ogawa T, Suzuki K, Van Meerbeek B, Okazaki M
Dent. Mater. J. 25:645‒649 (2006)

Detailed consideration of physicochemical properties of CO3 apatites as biomaterials in relation to carbonate content using ICP, X-ray, diffraction, FT-IR, SEM, and HR-TEM
Yokota R, Hayashi H, Hirata I, Miake Y, Yanagisawa T, Okazaki M
Dent. Mater. J. 25:597‒603 (2006)

Development of surface plasmon resonance imaging apparatus for high-throughput study of protein-surface interactions
Arima Y, Ishii R, Hirata I, Iwata H
e-J. Surf. Sci. Nanotech. 4:201‒207 (2006)

2005

A thin carboxymethyl cellulose culture substrate for the cellulase-induced harvesting of an endothelial cell sheet
Ko I-K, Kato K, Iwata H
J. Biomater. Sci. Polym. Ed. 16:1277–1292 (2005)

Layer-by-layer assembly of poly(ethyleneimine) and plasmid DNA onto transparent indium-tin oxide electrodes for temporally- and spatially-specific gene transfer
Yamauchi F, Kato K, Iwata H
Langmuir 21:8360–8367 (2005)

Immobilization of histidine-tagged recombinant proteins onto micropatterned surfaces for cell-based functional assays
Kato K, Sato H, Iwata H
Langmuir 21:7071–7075 (2005)

Parallel analysis of multiple surface markers expressed on rat neural stem cells using antibody microarrays
Ko I-K, Kato K, Iwata H
Biomaterials 26:4882–4891 (2005)

Antibody microarray for correlating cell phenotype with surface marker
Ko I-K, Kato K, Iwata H
Biomaterials 26:687–696 (2005)

Advantages of TOF-SIMS analysis of hydroxyapatite and fluorapatite in comparison with XRD, HR-TEM and FT-IR
Okazaki M, Hirata I, Matsumoto T, Takahashi J
Dent. Mater. J. 24:508‒514 (2005)

SEM observation of collagen fibrils secreted from the body surface of osteoblasts on a CO3apatite-collagen sponge
Hirata I, Nomura Y, Tabata H, Miake Y, Yanagisawa T, Okazaki M
Dent. Mater. J. 24:460‒464 (2005)

2004

Synthesis and characterization of stimuli-sensitive hydrogels having a different length of ethylene glycol chains carrying phosphate groups: loading and release of lysozyme
Nakamae K, Nishino T, Kato K, Miyata T, Hoffman AS
J. Biomater. Sci. Polym. Ed. 15:1435–1446 (2004)

Spatially and temporally controlled electroporation of adherent cells on plasmid DNA-loaded electrode
Yamauchi F, Kato K, Iwata H
Nucleic Acids Res. 32:e187 (2004)

Drug permeation through temperature-sensitive microfiltration membranes prepared from poly(vinylidene fluoride) with grafted poly(N-isopropylacrylamide) side chains
Ying L, Kang ET, Neoh KG, Kato K, Iwata H
J. Membr. Sci. 243:253–262 (2004)

Adsorption of enantiomeric poly(lactide)s on surface-grafted poly(L-lactide)
Tretinnikov ON, Kato K, Iwata H
Langmuir 20:6748–6753 (2004)

Micropatterned, self-assembled monolayers for fabrication of transfected cell microarrays
Yamauchi F, Kato K, Iwata H
Biochim. Biophys. Acta, General Subjects 1672:138–147 (2004)

Self-assembled monolayers

Kato K

Encyclopedia of Biomater. Biomed. Eng. 2004, Marcel Dekker, Inc., New York, NY, U.S.A., pp. 1331–1339

Simple method for preparation of ultra-thin poly(N-isopropylacrylamide) hydrogel layers and characterization of their thermo-responsive properties
Hirata I, Okazaki M, Iwata H
Polymer 45:5569‒5578 (2004)

Osteoblast proliferation behavior and bone formation on and in CO3apatite-collagen sponges with a porous hydroxyapatite frame
Tieliewuhan Y, Hirata I, Sasaki A, Minagi H, Okazaki M
Dent. Mater. J. 23:258‒264 (2004)

Characterization of CO3Ap-collagen sponges using X-ray high-resolution microtomography
Itoh M, Shimazu A, Hirata I, Yoshida Y, Shintani H, Okazaki M
Biomaterials 25:2577‒2583 (2004)

2003

Polymer surface with graft chains

Kato K, Uchida E, Kang ET, Uyama Y, Ikada Y

Prog. Polym. Sci. 28:209–259 (2003)

Deposition of complement protein, C3b, on mixed self-assembled monolayers carrying surface hydroxyl and methyl groups studied by surface plasmon resonance
I. Hirata, Y. Murakami, E. Kitano, H. Kitamura, Y. Ikada, H. Iwata
J. Biomed. Mater. Res. 66A:669‒676 (2003)

Investigation on light-addressable potentiometric sensor as a possible cell-semiconductor hybrid
A. B. Ismail, T. Yoshinobu, H. Iwasaki, H. Sugihara, T. Yukimasa, I. Hirata, H. Iwata
Biosens. Bioelectron. 18:1509‒1514 (2003)

2002

Hydroxyapatite deposition onto polymer surfaces

K. Kato, O. N. Tretinnikov, Y. Ikada

Biomimetic Calcium Phosphate Coatings H.B. Wen ed., 2002, Research Signpost, Trivandrum, India, pp. 15–29

2001

The interplay between surface micro-topography and -mechanics of type I collagen fibrils in air and aqueous media: An atomic force microscopy study
Kato K, Bar G, Cantow HJ
Eur. Phys. J. E 6:7–14 (2001)

Glistening formation in an AcrySof lens initiated by spinodal decomposition of the polymer network by temperature change
Kato K, Nishida M, Yamane H, Nakamae K, Tagami Y, Tetsumoto K
J. Cataract Refract. Surg. 27:1493–1498 (2001)

Synthesis of bioadhesive hydrogels from chitin derivatives
Zhao X, Kato K, Fukumoto Y, Nakamae K
Int. J. Adhesion Adhesives 21:227–232 (2001)

2000

Optical and atomic force microscopy of an explanted AcrySof intraocular lens with glistenings
Dogru M, Tetsumoto K, Tagami Y, Kato K, Nakamae K
J. Cataract Refract. Surg. 26:571–575 (2000)

Collagen immobilization onto the surface of artificial hair for improving the tissue adhesion
Kato K, Kikumura Y, Yamamoto M, Tomita N, Yamada S, Ikada Y
J. Adhes. Sci. Technol. 14:635–650 (2000)

Surface modification of Si3N4coated silicon plate for investigation of living cells
Hirata I, Iwata H, Ismail AB, Iwasaki H, Yukimasa T, Sugihara H
Jpn. J. Appl. Phys. 39, 6441‒6442 (2000)

Study of complement activation on welldefined surfaces using surface plasmon resonance
Hirata I, Morimoto Y, Murakami Y, Iwata H, Kitano E, Kitamura H, Ikada Y
Colloids Surf. B: Biointerf. 18:285‒292 (2000)

Hydrophilic modification of a polyimide film surface
Zhu B, Iwata H, Hirata I, Ikada Y
J. Adhes. Sci. Technol. 14:351‒361 (2000)

1999

Preparation of DNA-immobilized immunoadsorbents for treatment of systemic lupus erythematosus
Zhu B, Iwata H, Kang D, Yu Y, Kato K, Ikada Y
J. Biomater. Sci. Polym. Ed. 10:341–350 (1999)

Surface oxidation of cellulose fibers by vacuum ultraviolet irradiation
Kato K, Vasilets VN, Fursa MN, Meguro M, Ikada Y, Nakamae K
J. Polym. Sci.: Part A: Polym. Chem. 37:357–361 (1999)

1998

Lysozyme loading and release from hydrogels carrying pendant phosphate groups
Nakamae K, Nizuka T, Miyata T, Furukawa M, Nishino T, Kato K, Inoue T, Hoffman AS, Kanzaki Y
J. Biomater. Sci. Polymer Ed. 9:43–53 (1998)

Surface modification of polymers by grafting

Uyama Y, Kato K, Ikada Y

Adv. Polym. Sci. 137:1–39 (1998)

Atomic force microscopic analysis of a porous membrane with pHsensitive molecular valves
H. Iwata, I. Hirata, Y. Ikada
Macromolecules 31:3671‒3678 (1998)

Photolysis of a fluorinated polymer film by vacuum ultraviolet radiation
V. N. Vasilets, I. Hirata, H. Iwata, Y. Ikada
J. Polym. Sci., Part A: Polym. Chem. 36:2215‒2222 (1998)

1997

Histologic and mechanical evaluation for bone bonding of polymer surfaces grafted with a phosphate-containing polymer
Kamei S, Tomita N, Tamai S, Kato K, Ikada Y
J. Biomed. Mater. Res. 37:384–393 (1997)

In situ hydroxyapatite crystallization for the formation of hydroxyapatite / polymer composites
K. Kato, Y. Eika, Y. Ikada
J. Mater. Sci. 32:5533–5543 (1997)

Ultrastructure of the interface between cultured osteoblasts and surface-modified polymer substrates
M. Yamamoto, K. Kato, Y. Ikada
J. Biomed. Mater. Res. 37:29–36 (1997)

Studies on tumor-promoting activity of polyethylene: Inhibitory activity of metabolic cooperation on polyethylene surfaces is markedly decreased by surface modification with collagen but not with RGDS peptide
R. Nakaoka, T. Tsuchiya, K. Kato, Y. Ikada, A. Nakamura
J. Biomed. Mater. Res. 35:391–397 (1997)

Polymeric supports for immunoadsorption

K. Kato, Y. Ikada

Recent Res. Devel. in Macromol. Res. 2:157–173 (1997)

Atomic force microscopic images of solvated polymer brushes

H. Iwata, I. Hirata, Y. Ikada

Langmuir 13:3063‒3066 (1997)

1996

Effect of the structure of bone morphogenetic protein carriers on ectopic bone regeneration
Yamamoto M, Kato K, Ikada Y
Tissue Eng. 2:315–326 (1996)

Deposition of a hydroxyapatite thin layer onto a polymer surface carrying grafted phosphate polymer chains
Kato K, Eika Y, Ikada Y
J. Biomed. Mater. Res. 32:687–691 (1996)

Surface modification and functionalization of polytetrafluoroethylene films
Kang ET, Tan KL, Kato K, Uyama Y, Ikada Y
Macromolecules 29:6872–6879 (1996)

Plasma treatment of polyaniline films: Effect on the intrinsic oxidation states
Kang ET, Kato K, Uyama Y, Ikada Y
J. Mater. Res. 11:1570–1573 (1996)

XPS Characterization of surface functionalized electroactive polymers
Loh FC, Tan KL, Kang ET, Kato K, Uyama Y, Ikada Y
Surf. Interface Anal. 24:597–604 (1996)

Immobilization of DNA onto a polymer support and its potentiality as immunoadsorbent
Kato K, Ikada Y
Biotechnol. Bioeng. 51:581–590 (1996)

1995

Surface graft polymerization of glycidyl methacrylate onto polyethylene and the adhesion with epoxy resin
Zhang J, Kato K, Uyama Y, Ikada Y
J. Polym. Sci.: Part A: Polym. Chem. 33:2629–2638 (1995)

Selective adsorption of proteins to their ligands covalently immobilized onto microfibers
Kato K, Ikada Y
Biotechnol. Bioeng. 47:557–566 (1995)

Protein adsorption onto ionic surfaces
Kato K, Sano S, Ikada Y
Colloids Surf. B: Biointerfaces 4:221–230 (1995)

Peroxide generation and decomposition on polymer surface
Kulik EA, Ivanchenko MI, Kato K, Sano S, Ikada Y
J. Polym. Sci.: Part A: Polym. Chem. 33:323–330 (1995)

1994

In vitro hydroxyapatite deposition onto a film surface-grafted with organophosphate polymer
Tretinnikov ON, Kato K, Ikada Y
J. Biomed. Mater. Res. 28:1365–1373 (1994)

1993

Introduction of functional groups onto the surface of polyethylene for protein immobilization
Sano S, Kato K, Ikada Y
Biomaterials 14:817–822 (1993)

Trypsin immobilization on to polymer surface through grafted layer and its reaction with inhibitors
Kulik EA, Kato K, Ivanchenko MI, Ikada Y
Biomaterials 14:763–769 (1993)

EGF-His_Langmuir

Biomaterials 2008

Biomaterials 2007

Biomaterials 2013

Sci Rep 2020

Biotechnol Bioeng 2020

Bioconjug Chem 2009

Biomaterials 2011

Biomaterials 2007_2

ACS AMI 2015

Biomaterials 2005-1

iPS_Komura_2015

NSC in collagen_2

NSC in collagen_1

Array based screen_2011

Egawa

Artificial lymphoid

BDNF

ACS Appl Mater Interf 2009

siRNA_1

Multifunctional chimeras_2008

Keratin

siRNA_2

Anal Chem 2007

FLK-1_Yamauchi

Au NP on collagen

Combinatorial_Nakajima

Biomaterias 2005_2

Electroporation

Department of Biomaterials

Graduate School of Biomedical and Health Sciences, Hiroshima University

Publications

2024